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The Global Insight

Which of the following are part of the venous thrombosis Triad

Author

Matthew Martinez

Updated on April 01, 2026

Over a century ago, Rudolf Virchow

What are the components of Virchows Triad?

The three factors of Virchow’s triad include intravascular vessel wall damage, stasis of flow, and the presence of a hypercoagulable state.

Why is it called Virchow's triad?

Virchow’s triadDifferential diagnosisthrombosis

What is hypercoagulability in Virchows Triad?

The Virchow triad identifies the three underlying factors that are thought to contribute to thrombosis: hypercoagulability, hemodynamic dysfunction (ie, stasis—from immobilization or peripheral venous obstruction—or turbulence), and endothelial injury/dysfunction.

What is a venous stasis?

Venous stasis involves an inflammation of the skin in the lower legs as a result of chronic venous insufficiency. If the valves or walls of the veins in the legs are not working properly, it is difficult for blood to circulate from the legs back to the heart.

What does Hypercoagulability mean?

Introduction. Hypercoagulability or thrombophilia is the increased tendency of blood to thrombose. A normal and healthy response to bleeding for maintaining hemostasis involves the formation of a stable clot, and the process is called coagulation.

How does venous thrombosis form?

Causes. VTE occurs in the veins that carry blood to your heart. A deep vein thrombosis may occur if the flow of blood slows down in your body’s deep veins, if something damages the blood vessel lining, or if the makeup of the blood itself changes so that blood clots form more easily.

What is D dimer?

D-dimer is a protein fragment (small piece) that’s made when a blood clot dissolves in your body. Blood clotting is an important process that prevents you from losing too much blood when you are injured. Normally, your body will dissolve the clot once your injury has healed.

How does venous stasis cause DVT?

In the deep veins of the leg, if the blood flow is slow, or the vein wall is damaged / diseased or the blood itself is more prone to clot (thicker blood) then a clot forming in the vein becomes more likely.

What is Phlegmasia Cerulea Dolens?

Phlegmasia cerulea dolens is an uncommon, severe form of deep venous thrombosis (blood clots in the vein). It most often occurs in the upper leg.

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What is the ICD 10 code for venous stasis?

Venous insufficiency (chronic) (peripheral) I87. 2 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.

Is DVT venous or arterial?

Venous thromboembolism (VTE) is the most common vascular disease after acute myocardial infarction and stroke. It is represented by two main clinical events: deep venous thrombosis (DVT) and pulmonary embolism (PE), which often constitute an unique clinical picture in which PE follows DVT.

Why does venous stasis occur?

Chronic venous insufficiency (CVI) is a condition that occurs when the venous wall and/or valves in the leg veins are not working effectively, making it difficult for blood to return to the heart from the legs. CVI causes blood to “pool” or collect in these veins, and this pooling is called stasis.

What is pathogenesis of thrombosis?

The pathogenesis of thrombosis involves consideration of two processes: atherosclerosis and thrombosis. Atherosclerosis is a prolonged process in which interaction of lipids and the haemostatic system produces focal lesions at sites of turbulence in arteries.

What's a thrombosis?

Thrombosis occurs when blood clots block your blood vessels. There are 2 main types of thrombosis: Venous thrombosis is when the blood clot blocks a vein. Veins carry blood from the body back into the heart. Arterial thrombosis is when the blood clot blocks an artery.

What are the 3 stages of blood clotting?

1) Constriction of the blood vessel. 2) Formation of a temporary “platelet plug.” 3) Activation of the coagulation cascade. 4) Formation of “fibrin plug” or the final clot.

Which of the following is a hypercoagulable state?

What is a hypercoagulable state? A hypercoagulable state, also known as thrombophilia, is an increased tendency to develop blood clots (thrombosis) due to the presence of one or more predisposing factors, which can either be inherited or acquired.

What are hypercoagulable states?

Hypercoagulable states are clinical disorders of the blood that increase the patient’s risk for developing thromboembolic disease. A risk factor (inherited or acquired) for the development of a thrombus can be identified in more than 80% of patients with a clot, and there may be multiple factors present.

What does positive D-dimer mean?

A D-dimer test is a blood test that checks for, or monitors, blood-clotting problems. A positive test means the D-dimer level in the body is higher than normal and suggests someone might have blood clots.

What is elevated D-dimer level?

An elevated D-dimer level is not normal. It’s usually found after a clot has formed and is in the process of breaking down. If you are having significant formation and breakdown of blood clot in your body, your D-dimer may be elevated. A negative D-dimer test means that a blood clot is highly unlikely.

What is high D-dimer?

What does a high D-dimer test result mean? If your results reveal that you have higher-than-normal levels of D-dimer in your blood, it may mean that you have a blood clotting condition. A D-dimer test can’t determine the type of blood clotting condition you may have or where the blood clot(s) is in your body.

What causes Phlegmasia Cerulea Dolens?

Power Doppler sonography of the left common femoral vein shows resolution of the thrombus 7 days after thrombolysis. Phlegmasia cerulea dolens is a rare syndrome caused by diffuse venous thrombosis that is characterized by sudden pain, swelling, purple ecchymosis, and arterial ischemia with loss of distal pulses.

What causes Phlegmasia Alba Dolens?

Phlegmasia alba dolens, which translates to “painful white inflammation,” occurs when venous thrombosis progresses to a massive occlusion of the major deep venous system of the leg, but without ischemia as collateral veins are still patent.

What is venous gangrene?

Venous gangrene (VG) is defined as a clinical triad of skin necrosis and discolouration, documented evidence of venous thromboembolism (VTE) and presence of palpable or doppler- identifiable arterial pulsation. Venous gangrene is rare condition which is associated with poor prognosis in cancer patients.

What is the ICD 10 code for venous stasis ulcers?

Rationale: Since the ulcer was caused by varicose veins, the I83. 0- category is the appropriate place to begin, and I83. 018 specifies the location of the ulcer.

What is the ICD 10 code for PVD?

Other specified peripheral vascular diseases The 2022 edition of ICD-10-CM I73. 89 became effective on October 1, 2021.

Is venous insufficiency the same as PVD?

PVD occurs when disease affects any of the vessels outside of your heart, wherever they happen to be — in your arms, legs, brain or anywhere else. A common type of PVD is venous insufficiency, which occurs when the valves in the leg veins don’t shut properly during blood’s return to the heart.

Is a PE venous or arterial?

Pulmonary embolism is a blockage in one of the pulmonary arteries in your lungs. In most cases, pulmonary embolism is caused by blood clots that travel to the lungs from deep veins in the legs or, rarely, from veins in other parts of the body (deep vein thrombosis).

What is the most common thrombosis?

The most common type of blood clot is called deep vein thrombosis or DVT. This is a clot in one of the deep veins of the body, usually in the leg.

What is vascular thrombosis?

Acute vascular thrombosis occurs when a blood clot obstructs a vein. Veins carry blood back toward the heart after the blood has been pumped to different parts of the body and the oxygen used. Blockages in these vessels can slow or even stop blood flow and cause serious consequences.

What is turbulence and stasis?

Abnormal Blood Flow: Stasis and turbulence are alterations in normal blood flow, which can cause endothelial injury. 2. Aneurisms (aortic and arterial dilations) cause local turbulence; a dilated atrium in the presence of atrial fibrillation is a site of significant stasis that may provoke thrombus development.