What are the side effects of neo synephrine
Mia Horton
Updated on April 04, 2026
severe sneezing, runny or stuffy nose, redness or swelling in your nose, or other worsening nasal symptoms (may be a sign of overuse of Neo-Synephrine Nasal);severe stinging, burning, or irritation inside your nose;severe dizziness, restless feeling, nervousness, or insomnia;
What is an expected side effect when taking Neo-Synephrine?
Common side effects of Neo-Synephrine include burning, stinging, pain, increased redness of the eye, tearing or blurred vision, headache, tremor, nausea, sweating, nervousness, dizziness, drowsiness, dryness in the nose, runny nose, and sneezing.
How long does Neo-Synephrine stay in your system?
Several studies have shown that the half-life of p-synephrine is between 2 and 3 hours.
Is Neo-Synephrine safe?
The active ingredient in Neo-Synephrine® is phenylephrine hydrochloride. Phenylephrine hydrochloride is a rapidly acting topical nasal decongestant, which is recognized as safe and effective by the FDA.Does Neo-Synephrine raise blood pressure?
It is a vasoconstrictor medication, structurally similar to epinephrine and ephedrine. Vasoconstriction increases blood pressure. Phenylephrine increases blood pressure and heart rate without affecting heart rhythm.
What are the ingredients in Neo-Synephrine?
Active Ingredient/Active MoietyIngredient NameBasis of StrengthStrengthPHENYLEPHRINE HYDROCHLORIDE (UNII: 04JA59TNSJ) (PHENYLEPHRINE – UNII:1WS297W6MV)PHENYLEPHRINE HYDROCHLORIDE1 g in 100 mL
Is Neo-Synephrine addictive?
But relief provided by nasal spray decongestants like Afrin and Neo-Synephrine comes at a price: the risk of rebound congestion caused by overuse and, for some people, a vicious cycle of overuse and dependence that feels like an addiction. “It works so well that you tend to keep using it,” says Dr.
Can I take phenylephrine at night?
It can affect the quality of your sleep, so you can’t take it too close to going to bed. Can raise blood pressure so check with your doctor before using it if you have high blood pressure or other heart conditions. Sudafed (Pseudoephedrine) isn’t as effective after using it for more than 4 days straight.How is neo-synephrine administered?
NEO-SYNEPHRINE is generally injected subcutaneously, intramuscularly, slowly intravenously or in dilute solution as a continuous intravenous infusion.
When should you not take a decongestant?People who have conditions such as diabetes, benign prostatic hyperplasia (BPH), ischemic heart problems, thyroid disorders, glaucoma and seizures generally should avoid using nasal decongestants.
Article first time published onHow often can I take Neosynephrine?
Neo-Synephrine Nasal is usually used every 4 hours. Follow the directions on the medicine label. Never use more of this medicine than directed on the label or prescribed by your doctor. Using this medicine too long can damage the lining of your nasal passages and lead to chronic nasal congestion.
Does neo cause bradycardia?
Phenylephrine can affect cardiac output in several ways: Reflex bradycardia: Increased blood pressure may trigger the carotid baroreflex, causing a decreased heart rate which reduces cardiac output.
Does synephrine fail drug test?
The primary active ingredient in bitter orange is synephrine. Previous reports have documented false-positive results from ephedrine with urine amphetamine assays.
Is Nasal Spray bad for you?
Prolonged use can lead to rebound swelling and, ironically, long-term stuffiness. Steroid sprays, while not habit forming, don’t show any increased benefit if used more than once a day. Also, any nasal spray can irritate the tissue inside the nose and cause nosebleeds.
Is Neo synephrine and phenylephrine the same?
NEO-SYNEPHRINE hydrochloride, brand of phenylephrine hydrochloride ophthalmic solution, is a sterile solution used as a vasoconstrictor and mydriatic for use in ophthalmology.
What happens when you stop using nasal spray?
Decongestants shrink the blood vessels in your nasal passages. When the drug wears off, they swell up again. This causes immediate withdrawal congestion. According to the National Institute on Drug Addiction , there’s a difference between physical drug dependence and addiction.
Why is Afrin so bad for you?
This rebound nasal congestion is known as rhinitis medicamentosa (RM) that is caused by the extended use of topical decongestants. Long-term use of oxymetazoline may cause the nasal tissues to permanently enlarge and not respond to medications. It may need surgical intervention to cure the blocked nose symptoms.
How do I quit Afrin?
- STOP the nasal decongestant spray use immediately (more rarely, one can try to wean off the afrin by diluting the concentration with saline by 25% on a daily basis)
- High dose prednisone starting at 60mg tapered slowly over ~2 weeks.
- Start steroid nasal spray AND anthistamine nasal spray use.
Who owns Neo synephrine?
Neo-Synephrine Regular Strength – B.F. Ascher & Company, Inc.
What does Neo synephrine do in the body?
This medication is used for temporary relief of congestion in the nose caused by various conditions including the common cold, sinusitis, hay fever, and allergies. It works by narrowing the blood vessels in the nose area, reducing swelling and congestion.
Can Nurses push Neosynephrine?
May be administered IV direct or by IV infusion by a nurse in Adult Critical Care. May be titrated by a nurse in Adult Critical Care.
Can Neosynephrine cause bradycardia?
Results: Phenylephrine is a pure vasopressor that only has activity at the alpha-adrenergic receptors. Because it does not have any beta agonist properties to support cardiac output, activation of the baroreceptor may result in bradycardia. As noted in our case, this may persist for > 24 hours.
Is phenylephrine bad for high blood pressure?
To keep your blood pressure in check, avoid over-the-counter decongestants and multisymptom cold remedies that contain decongestants — such as pseudoephedrine, ephedrine, phenylephrine, naphazoline and oxymetazoline. Also, check the label for high sodium content, which can also raise blood pressure.
Can phenylephrine cause anxiety?
Two commonly-used decongestants are pseudoephedrine (Sudafed) and phenylephrine (Sudafed PE). These medications work great to clear nasal passages and help us breathe better. But to our bodies, they look very similar to the stimulants discussed earlier and can have the same side effects, including anxiety.
Can phenylephrine cause high blood pressure?
Topical nasal decongestants such as Afrin (oxymetazoline), Neo-Synephrine (phenylephrine), Privine (naphazoline), and Vicks VapoRub Inhaler (l-desoxyephedrine/levmetamfetamine) can also cause an increase in blood pressure.
How do I stop sinus drainage in my throat?
- Prop up your head. Elevate your head to let gravity drain mucus from your nasal passages. …
- Drink fluids, especially hot fluids. Drink a lot of fluids to thin out mucus. …
- Gargle saltwater. …
- Inhale steam. …
- Use a humidifier. …
- Nasal rinse. …
- Avoid alcohol and cigarette smoke. …
- GERD home remedies.
Is Vicks a decongestant?
Vicks VapoRub (VVR) is not a decongestant. In other words, it doesn’t actually relieve nasal or chest congestion. However, it might make you feel less congested. When applied to your skin, VVR releases a strong minty odor due to the menthol that’s included in the ointment.
What is the best decongestant to take at night?
SUDAFED PE® Sinus Congestion Day + Night. From the #1 pharmacist recommended brand among oral OTC decongestants, these maximum strength tablets provide powerful relief of sinus and nasal congestion and sinus pressure relief, during both day and night.
How do you mix Neosynephrine drip?
Add 10 mg of the drug (1 mL of 1 percent solution) to 500 mL of Dextrose Injection, USP or Sodium Chloride Injection, USP (providing a 1:50,000 solution). To raise the blood pressure rapidly, start the infusion at about 100 mcg to 180 mcg per minute (based on 20 drops per mL this would be 100 to 180 drops per minute).
How long can you use phenylephrine nose spray?
Do not use phenylephrine nasal spray for longer than 3 days. If your symptoms do not get better after 3 days of treatment, stop using phenylephrine and call your doctor. Phenylephrine nasal spray is only for use in the nose.
Does norepinephrine increase or decrease heart rate?
Together with adrenaline, norepinephrine increases heart rate and blood pumping from the heart. It also increases blood pressure and helps break down fat and increase blood sugar levels to provide more energy to the body.