What are the side effects of Janumet XR
David Craig
Updated on March 22, 2026
Nausea, vomiting, stomach upset, diarrhea, headache, or a metallic taste in the mouth may occur. A tablet may also appear in your stool. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
What is the best time of day to take Janumet XR?
It is better to take JANUMET XR with your evening meal. tablets before swallowing. If you cannot swallow JANUMET XR tablets whole, tell your doctor. You may see something that looks like the JANUMET XR tablet in your stool (bowel movement).
Is Janumet bad for kidneys?
You should not use Janumet if you have severe kidney disease or diabetic ketoacidosis (call your doctor for treatment with insulin). Janumet may cause a serious condition called lactic acidosis.
Is Janumet stronger than metformin?
Cimetidine (Tagamet), by decreasing the elimination of metformin from the body, can increase the level of metformin in the blood by 40%.Is Janumet bad for the heart?
Januvia and Janumet are similar medications used in the treatment of Type 2 diabetes. Common side effects include headache and flu-like symptoms. Some of the potential serious side effects include lactic acidosis, heart problems and pancreatitis.
Can I stop taking Janumet XR?
Do not stop taking JANUMET XR without talking to your doctor. Follow all directions given to you by your doctor and pharmacist carefully. If you do not understand the instructions on the box, ask your doctor or pharmacist for help.
What is the difference between Janumet and Janumet XR?
Janumet and Janumet XR are both prescription medications designed to be used along with diet and exercise to help control blood sugar levels in adults with type 2 diabetes. The difference is that Janumet is taken twice daily, while Janumet XR (extended-release) is taken only once daily.
What is the best medication for diabetes?
Metformin (Fortamet, Glumetza, others) is generally the first medication prescribed for type 2 diabetes. It works primarily by lowering glucose production in the liver and improving your body’s sensitivity to insulin so that your body uses insulin more effectively.Does janumet make you pee more?
Symptoms of high blood sugar (hyperglycemia) include thirst, increased urination, confusion, drowsiness, flushing, rapid breathing, and fruity breath odor. If these symptoms occur, tell your doctor right away.
How long does it take for Janumet XR to work?Depending on the dose, the medication starts working within 4 to 5 days, but the full effects of Janumet (sitagliptin / metformin) can take up to a few weeks in lowering your blood sugar and improving your A1c level.
Article first time published onCan you drink alcohol while taking Janumet?
Consumer information for this interaction is not currently available. GENERALLY AVOID: Alcohol can potentiate the effect of metformin on lactate metabolism and increase the risk of lactic acidosis. In addition, alcohol may cause hypoglycemia or hyperglycemia in patients with diabetes.
How do I get rid of Janumet?
- maintaining a healthy weight.
- getting more exercise.
- reducing your intake of carbohydrates.
- modifying your diet to include low-glycemic carbohydrates.
- stopping smoking tobacco in any form.
Can janumet cause joint pain?
Joint pain. Some people who take medicines called DPP-4 inhibitors, one of the medicines in JANUMET, may develop joint pain that can be severe. Call your doctor if you have severe joint pain.
What is the safest diabetic medication?
Metformin is still the safest and most effective type 2 diabetes medication, said Bolen.
Is it OK to take JANUMET XR twice a day?
Recommended Dosing Patients taking two JANUMET XR tablets should take the two tablets together once daily. Individualize the dosage of JANUMET XR on the basis of the patient’s current regimen, effectiveness, and tolerability.
What is a good alternative to janumet?
Drugs in the sulfonylureas class, like Glucotrol (glipizide), glyburide, and Amaryl (glimepiride) work to help your body stimulate more insulin, and are commonly used for the treatment of diabetes. All of these come in pill form, just like Janumet, so you don’t have to worry about using an injectable.
Can you take Janumet twice a day?
Janumet should be given twice daily with meals to reduce the gastrointestinal adverse reactions associated with metformin.
How effective is Janumet XR?
Janumet has an average rating of 6.1 out of 10 from a total of 53 ratings for the treatment of Diabetes, Type 2. 45% of reviewers reported a positive effect, while 30% reported a negative effect.
What happens when you stop taking Janumet?
Janumet may cause a very rare (may affect up to 1 in 10,000 people), but very serious side effect called lactic acidosis (see section “Warnings and precautions”). If this happens, you must stop taking Janumet and contact a doctor or the nearest hospital immediately, as lactic acidosis may lead to coma.
Is janumet considered insulin?
Janumet (sitagliptin / metformin) This form of insulin is one of the few medications in its class that you can get without a prescription, but it’s expensive. Lowers your blood sugar. Janumet is a combination of two anti-diabetic medicines that work better together, but is available as brand only.
What is the highest blood sugar level that is safe?
Normal blood sugar levels for adultsBefore meal70-1301-2 hours after eatingLess than 180Bedtime100-140
How do you bring your blood sugar down quickly?
- whole grains.
- fruits.
- vegetables.
- lean proteins.
What is the new pill for diabetes?
FRIDAY, Sept. 20, 2019 (HealthDay News) — A new pill to lower blood sugar for people with type 2 diabetes was approved by the U.S. Food and Drug Administration on Friday. The drug, Rybelsus (semaglutide) is the first pill in a class of drugs called glucagon-like peptide (GLP-1) approved for use in the United States.
Can I just stop taking JANUMET?
Do not take JANUMET if: need to be stopped for a short time. Talk to your doctor about when you should stop JANUMET and when you should start JANUMET again.
Does Janumet XR contain metformin?
JANUMET tablets contain 2 prescription medicines: sitagliptin (JANUVIA®) and metformin. Once-daily prescription JANUMET XR tablets contain sitagliptin (the medicine in JANUVIA®) and extended-release metformin.
What are the negative effects of Januvia?
The most common side effects of JANUVIA include upper respiratory infection, stuffy or runny nose and sore throat, and headache. JANUVIA may have other side effects, including stomach upset and diarrhea, swelling of the hands or legs, when JANUVIA is used with metformin and rosiglitazone (Avandia ®).
Can janumet cause blurry vision?
Janumet does not usually cause low blood sugar (hypoglycemia). Low blood sugar may occur if Janumet is prescribed with other anti-diabetic medications. Symptoms of low blood sugar include sudden sweating, shaking, fast heartbeat, hunger, blurred vision, dizziness, or tingling hands/feet.
Can a diabetic drink wine or beer?
The best types of alcohol for people with diabetes are those with a low sugar or carb content. That includes light beers, red and white wines, distilled spirits, and low carb cocktails, as long as you avoid sugary juices or syrups.
Can walking cure diabetes?
Research studies have shown that walking can be beneficial in bringing down blood glucose and therefore improving diabetes control. In a study involving people with type 1 diabetes, participants were assigned to either take a 30 minute walk after eating or have the same meal but remain inactive.
What medications should diabetics avoid?
- Azole antifungals.
- Certain antibiotics, including rifampin and isoniazid.
- Some high blood pressure medicines, such as calcium channel blockers, beta-blockers, and thiazide diuretics.
- Corticosteroids.
- Estrogen.
- Nicotinic acid.
- Oral contraceptives.
- Phenothiazines.
How can I reverse diabetes naturally?
- Avoid ALL refined carbohydrates. …
- Avoid ALL added sugar. …
- Avoid ALL sweet drinks. …
- Do not be scared of good quality, healthy, natural fat – avocados, olives, almonds etc. …
- Do not waste your energy counting calories. …
- FEED YOUR GUT BUGS, not just yourself.